|
Symbol Name ID |
Tsc1
TSC complex subunit 1 MGI:1929183 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal morphology of female internal genitalia |
| Disease(s) Associated with TSC1 | |
| lymphangioleiomyomatosis |
| Mouse Phenotypes | reproductive system phenotype |
abnormal oocyte morphology |
oocyte degeneration |
decreased male germ cell number |
increased Sertoli cell proliferation |
abnormal ovarian follicle morphology |
decreased primordial ovarian follicle number |
increased atretic ovarian follicle number |
impaired ovarian folliculogenesis |
abnormal testis morphology |
abnormal seminiferous tubule morphology |
abnormal seminiferous tubule epithelium morphology |
abnormal Sertoli cell morphology |
decreased testis weight |
small testis |
abnormal ovary physiology |
premature ovarian failure |
increased uterus leiomyoma incidence |
abnormal oviduct morphology |
dilated oviduct |
endometrium hyperplasia |
abnormal myometrium morphology |
abnormal spermatogenesis |
short diestrus |
prolonged estrus |
failure of embryo implantation |
female infertility |
reduced female fertility |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Tsc1tm1Hin/Tsc1+ | |||||||||||||||||||||||||||||
| Tsc1tm1Djk/Tsc1tm1Djk Tg(Gdf9-icre)5092Coo/? (conditional) |
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| Amhr2tm3(cre)Bhr/Amhr2+ Tsc1tm1Djk/Tsc1tm1Djk (conditional) |
* | ||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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